Use INFeD only in patients in whom clinical and laboratory investigations have established an iron deficient state not amenable to oral iron therapy. Avoid or Use Alternate Drug. Iron Sucrose (Ferogen): Indications, Dosage, Administration - Medcrine Venofer / Products / American Regent It is usually given slowly over 2 to 5 minutes or as directed by your doctor. The prevention and treatment of iron deficiency is a major public health goal, especially in women, children, and individuals in low-income countries. DICP. Use Caution/Monitor. Iron Deficiency in Heart Failure - Home - American College of Cardiology Maximum single dose of iron sucrose to be given at a time in Non-dialysis CKD patients is 500 mg but with limited experience. Next Steps Evidence Creator Insights Dr. Andreas M. Ganzoni About the Creator Ensure the Intravenous Iron Checklist (see trust guideline) has been completed. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). Ganzoni AM. Initial infusion rate. Avoid or Use Alternate Drug. The factor 2.4 is derived from the following assumptions: a) Blood volume 70 ml/kg of body weight ~7% of body weight b) Iron content of hemoglobin 0.34% Factor 2.4 = 0.0034 x 0.07 x 10000 (conversion for g/dL) Ganzoni AM. DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest. Give each dose as 750 mg for a total cumulative dose not to exceed 1500 mg of iron per course. Schweiz Med Wochenschr; 100(7):301-3. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. The dosage of iron sucrose is expressed in mg of elemental iron. Intravenous therapy is preferred for urgent intervention and when oral iron cannot be absorbed or the patient suffers from chronic renal impairment. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abacb7fa-2fc2-471e-9200-944eeac8ca2a. iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. Intermediate calculations: -Blood volume (dL) = [65 (mL/kg) x body weight (kg)] / 100 (mL/dL) -Hgb deficit (g/dL) = 14.0 - patient hgb conc. iron sucrose decreases levels of moxifloxacin by inhibition of GI absorption. The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 Hb in g/dL) x 2.145, Volume of product required in mL = Iron deficit in mg / C in mg/mL. Venofer must only be administered intravenously either by slow injection or by infusion. iron sucrose increases levels of calcium citrate by enhancing GI absorption. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Hypotension following administration of Venofer may be related to rate of administration and/or total dose delivered. The usual adult total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Manufacturer advises for slow intravenous injection ( Venofer ), give undiluted at a rate of 1 mL/minute; do not exceed 10 mL (200 mg iron) per injection. Applies only to oral form of both agents. Iron sucrose: 20 mg/mL. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. Venofer (iron sucrose) Uses, Dosage, Side Effects - Drugs.com 200-800 mg/kg (2-8 mL/kg) every 3-4 weeks. A maximum dose of 1000 mg iron can be delivered intravenously over 15 minutes, which may make it a suitable treatment for iron-deficiency anaemia outside of the hospital setting. Minor/Significance Unknown. calcium carbonate decreases levels of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. Administer Feraheme as an intravenous infusion in 50-200 mL 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP over at least 15 minutes. Suggested regime: Prescribing instructions Prescribing a single/first dose: A healthcare provider will give you this injection. Applies only to oral form of both agents. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. Deferasirox chelates iron. Alldredge BK, Corelli RL, Ernst ME, Guglielmo BJ, eds. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling (16.2).] Dose. calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. Venofer (Iron Sucrose Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Applies only to oral form of both agents. Either increases effects of the other by pharmacodynamic synergism. Administer Venofer early during the dialysis session (generally within the first hour). You may report side effects to Health Canada at 1-866-234-2345. In less advanced cases of iron deficiency, increases in dietary intake of iron may be sufficient. When to Use Weight lbs Target hemoglobin g/dL Actual hemoglobin g/dL Iron stores Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg mg Result: Please fill out required fields. Individual doses of 2 mL or less may be given on a daily basis until the calculated total amount required has been reached. March 2, 2015 [IRON SUCROSE REQUIREMENT CALCULATION FOR SEVERE ANEMIA] DPMU Anantapuramu | National Health Mission 1 Formula for calculating the required dose of Iron sucrose 2.4 X Pre-pregnancy Weight in Kgs X Hb% deficit{11-actual Hb%} in mgs Plus Iron required to replenish the iron stores = 500mg Prepregnancy Weight = 45 kgs . Administer Injectafer intravenously, either as an undiluted slow intravenous push or by infusion. Separate dosing of tetracyclines from these products. Consult your doctor before breast-feeding. There are four fields that need to be completed: Weight body weight is used to establish iron deficit and is also taken into account when estimating the iron stores. Drug Des Devel Ther; 5: 5160. IDA symptoms vary, may not be specific and include tiredness, weakness, shortness of breath. Recommended starting dose 1 Aranesp is dosed at 2.25 mcg/kg SC QW or 500 SC Q3W 1 (SC = subcutaneous) Before initiating 1: Evaluate iron status; administer supplemental iron therapy as needed Correct or eliminate other causes of anemia Initiate 1: Only when Hb < 10 g/dL iron sucrose decreases levels of manganese by inhibition of GI absorption. Discuss the risks and benefits with your doctor.This medication passes into breast milk. Indications: Feraheme is indicated for the treatment of iron deficiency anemia (IDA) in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron or who have chronic kidney disease (CKD). UpToDate. Brand name: Venofer Drug class: Iron Preparations Chemical name: iron saccharate CAS number: 8047-67-4 Medically reviewed by Drugs.com on Oct 25, 2022. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. Use Caution/Monitor. Venofer® (iron sucrose) injection, USP is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Your doctor will do laboratory tests to monitor your response. PRECAUTIONS: Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Copyright 2021 GlobalRPH - Web Development by. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Use Caution/Monitor. iron sucrose increases levels of calcium chloride by enhancing GI absorption. Use (s): Iron deficiency anemia in patients with chronic kidney disease (CKD) Iron sucrose: 20 mg/mL. Minor/Significance Unknown. Methods: We reviewed the experience of our department between January, 2011 and February, 2014 with the use of intravenous iron sucrose in children 14 years of age who failed in oral iron therapy for iron deficiency anemia (IDA). Intravenous iron-dextran: therapeutic and experimental possibilities. 1. The above information is provided for general Monitor Closely (1)iron sucrose will decrease the level or effect of omadacycline by inhibition of GI absorption. Applies only to oral form of both agents. Each costs about $0.46 to $0.55 per mg of iron. Hemoglobin can be input in g/dL, g/L or mmol/L and refers to the amount of hemoglobin in the red blood cells. Applies only to oral form of both agents. Applies only to oral form of both agents. DOSAGE AND ADMINISTRATION: Venofer must only be administered intravenously either by slow injection or by infusion. iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Monitor Closely (1)cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. These adverse reactions have occurred up to 30 minutes after the administration of Venofer injection. Pain, swelling, or redness at the injection site may occur. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Parenteral iron supplementation. Applies only to oral form of both agents. A patients lean body weight (or actual body weight if less than lean body weight) should be utilized when determining dosage. Monitor Closely (1)vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. 1) Ganzoni AM. FERAHEME Dosing & Administration - Feraheme Use Caution/Monitor. Monitor Closely (1)nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. Data from Ferrlecit postmarketing spontaneous reports indicate that individual doses exceeding 125 mg may be associated with a higher incidence and/or severity of adverse events. Parenteral iron dose - UpToDate Privacy Policy, Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg. Intravenous iron sucrose for children with iron deficiency anemia: a Separate by at least 4 hours. Properly discard this product when it is expired or no longer needed. Calculation of Dosage of Nefrofer Total Iron Deficit (mg) Nefrofer (ml) = 20mg/ml Total Iron Deficit (mg) = Body weight (kg) x (Target Hb - Actual Hb) [g/l] x 0.24* + Depot Iron . There are four variables, all patient parameters, required in the iron deficiency calculator: The patients weight is used in the Ganzoni equation and also when establishing the iron stores. Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week. LBW = Lean body weight in kg. One dose IV Iron replacement | Monoferric I. Minor/Significance Unknown. Hemoglobin iron deficit = 60 x (14 - 8) x (2.145) = 772 mg iron. 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. Serious - Use Alternative (1)iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. This drug is available at a higher level co-pay. . PDF Highlights of Prescribing Information Contraindications- Venofer Calculation of total iron deficit for initial repletion: [29] Total cumulative dose (mg) = [Target Hb Actual Hb] weight (kg) 2.4 + [15 weight (kg)] *Hb in g/dl: 2. gymnema decreases levels of iron sucrose by inhibition of GI absorption. Last updated on Jun 1, 2022. Applies only to oral form of both agents. Venofer treatment may be repeated if necessary. Serious - Use Alternative (1)iron sucrose decreases levels of minocycline by inhibition of GI absorption. This information does not assure that this product is safe, effective, or appropriate for you. Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Iron Dextran Dosing Calculator (iron deficit). PDF Treatment Guideline - Gloucestershire Royal Hospital Minor (1)gymnema decreases levels of iron sucrose by inhibition of GI absorption. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. PDF Protocol for the use of Intravenous Iron Dextran (CosmoFer If you log out, you will be required to enter your username and password the next time you visit. Use Caution/Monitor. VENOFER (IRON SUCROSE INJECTION,USP) 100mg ELEMENTAL IRON - DailyMed dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. We'll do this entirely for free, as long as the calculator has applications for women's health. Use Caution/Monitor. Venofer is given as an infusion into a vein. The dose of Ferinject is based on calculation of ideal body weight and calculation of iron deficit using the Ganzoni formula. Iron metabolism needs to be balanced and bleeding, the major cause of iron deficiency (for instance in menstruation in females and chronic occult gastrointestinal bleeding) needs to be addressed. iron sucrose decreases levels of doxycycline by inhibition of GI absorption. Applies only to oral form of both agents. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. IV iron products (adults) - UpToDate Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. calcium gluconate decreases levels of iron sucrose by inhibition of GI absorption. Feraheme, when added to intravenous infusion bags containing either 0.9% Sodium Chloride Injection, USP (normal saline), or 5% Dextrose Injection, USP, at concentrations of 2-8 mg elemental iron per mL, should be used immediately but may be stored at controlled room temperature (25C 2C) for up to 4 hours or refrigerated (2-8 C) for up to 48 hours. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. (1970) Intravenous iron-dextran: therapeutic and experimental possibilities. IDA symptoms are often nonspecific and include tiredness, weakness, shortness of breath. Use Caution/Monitor. Minor/Significance Unknown. Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session. Serious - Use Alternative (1)iron sucrose decreases levels of doxycycline by inhibition of GI absorption. Iron Sucrose Monograph for Professionals - Drugs.com iron sucrose will decrease the level or effect of sarecycline by inhibition of GI absorption. If hypersensitivity reactions or signs of intolerance occur during administration, stop Venofer immediately. Venofer (iron sucrose) dose calculator | Calculosaurus.com The dosing of Monofer was performed according to the Simplified Table as described in section 4.2 above and dosing of iron sucrose was calculated according to Ganzoni and administered as 200 mg infusions. Before using, check this product visually for particles or discoloration. Minor/Significance Unknown. Untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia. Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products (such as Venofer) which may cause fetal bradycardia, especially during the second and third trimester. Do not mix iron sucrose with other medications or TPN solution. Applies only to oral form of both agents. Injection site discoloration has been reported following extravasation. Med J Aust; 193(9):525-32. No additional iron to replenish stores. Only administer Feraheme as an intravenous infusion over at least 15 minutes and only when personnel and therapies are immediately available for the treatment of anaphylaxis and other hypersensitivity reactions. calcium acetate decreases levels of iron sucrose by inhibition of GI absorption. https://www.uptodate.com/ (Requires subscription). Share cases and questions with Physicians on Medscape consult. The iron formulation choice remains for the clinician to make. commonly, these are "non-preferred" brand drugs. iron sucrose, benazepril. Monitor Closely (1)calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Serious - Use Alternative (1)iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. Use Caution/Monitor. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Serious - Use Alternative (1)iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. On the other hand, slow decreases, such as that in chronic occult gastrointestinal bleeding are often difficult to diagnose. Individual plans may vary Do not administer Venofer to patients with evidence of iron overload. US residents can call their local poison control center at 1-800-222-1222. 2.1 Dosage - Total dose infusion The dose calculation for CosmoFer is based on patients body weight according to the table below and is diluted in 500mLs of normal saline. Applies only to oral form of both agents. Dr. Ganzonis primary research is focused on iron deficiency and plasma iron transport. Avoid or Use Alternate Drug. Anemias. Drug class: Iron products. It should be recognized that iron storage may lag behind the appearance of normal blood morphology. All Rights Reserved. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If we don't have the calculator you need we'll try to make it for you and add it to the website. Baloxavir may bind to polyvalent cations resulting in decreased absorption. J Lab Clin Med. Applies only to oral form of both agents. Mode of Administration: Administer Venofer only intravenously by slow injection or by infusion. Contraindicated. Medicinal forms Parenteral iron product is iron sucrose (C = 20 mg elemental iron/mL). Treatment of iron deficiency anemia in adults - UpToDate 1 ,*. Objective. Monitor Closely (1)iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. Intravenous iron sucrose for children with iron deficiency failing to Ferric gluconate: 12.5 mg/mL Schrier SL, Mentzer WC, Landaw SA. Do Not Copy, Distribute or otherwise Disseminate without express permission. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. Minor/Significance Unknown.iron sucrose increases levels of calcium carbonate by enhancing GI absorption. PDF PRODUCT MONOGRAPH - pdf.hres.ca Monitor Closely (1)iron sucrose decreases levels of liothyronine by inhibition of GI absorption. The dosage of Venofer is expressed in mg of elemental iron. Human studies not conducted. Applies only to oral form of both agents. Deferasirox chelates iron. 4. iron sucrose increases levels of calcium carbonate by enhancing GI absorption. Most Applies only to oral form of both agents. nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. elemental iron (mg/ml) in the product being used: Where C= Applies only to oral form of both agents. Applies only to oral form of both agents. The recommended dosage of iron sucrose for repletion of iron deficiency in patients undergoing hemodialysis is 5ml of iron sucrose (100mg of elemental iron) delivered intravenously during the dialysis session. )If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Applies only to oral form of both agents. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. ONE DOSE. DOSAGE AND ADMINISTRATION: Oral iron should be discontinued prior to administration of INFeD. Applies only to oral form of both agents. Iron deficit - equation derivation: Assumptions: -Blood volume = 65 mL/kg -Hemoglobin conc target =14.0 g/dL -Deficits in body stores are ignored. Drug Dosing in Obesity Reference Table - ClinCalc.com 2010; 193(9):525-32. Either decreases levels of the other by inhibition of GI absorption. Minor/Significance Unknown. All you have to do is use the following formula: Liquid\ dose = Dose / Medicine\ concentration Liquid dose = Dose/M edicine concentration. Most adults require a cumulative dose of elemental iron of at least 1 g. Iron replenishment is usually doneintravenously, via iron-dextran, iron sucrose or iron carboxymaltose. commonly, these are "non-preferred" brand drugs or specialty Avoid or Use Alternate Drug. Applies only to oral form of both agents. The normal ranges are: for males 13.8 to 18.0 g/dL (138 to 180 g/L, or 8.56 to 11.17mmol/L) and for females 12.1 to 15.1 g/dL (121 to 151 g/L, or 7.51 to 9.37mmol/L). iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Maximum recommended single dose: 300 mg (See Prescriber's Orders). Adults and Children over 15 kg (33 lbs): Dose (mL) = 0.0442 (Desired Hb - Observed Hb) x LBW + (0.26 x LBW), Desired Hb = the target Hb in g/dl. DailyMed - VENOFER- iron sucrose injection, solution Applies only to oral form of both agents. Venofer (Iron Sucrose Injection): Uses, Dosage, Side Effects - RxList In key trials, ferric carboxymaltose increased Hb levels and replenished iron stores as effectively as IV iron sucrose . provider for the most current information. Applies only to oral form of both agents. Multiple placebo-controlled, randomized clinical trials have been conducted with IV iron in patients with New York Heart Association class II-III heart failure with an ejection fraction 45% who met criteria . Max Dose. Controlled studies in pregnant women show no evidence of fetal risk. Iron Sucrose - SlideShare A: Generally acceptable. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. VenAccess is a trademark of Vifor (International) Inc. Switzerland. Applies only to oral form of both agents. (See also Notes section. Transferrin saturation (TSAT) values increase rapidly after intravenous administration of iron sucrose; do not perform serum iron measurements for at least 48 hours after intravenous dosing. an automated flowchart approach. USES: This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Minor/Significance Unknown. Use Caution/Monitor. Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. Administer a test INFeD dose prior to the first therapeutic dose. Iron Sucrose - Injection - Alberta Fatal reactions have also occurred in situations where the test dose was tolerated. Applies only to oral form of both agents. Situation Analysis Market Size MAT Sales Cr LC MAT Share % MAT Gr % Total Pharma Market 9388.69 100 13.5 Iron Sucrose 11.18 93.81 37.65 Brand Company Saline MAT . Monitor for signs and symptoms of hypotension following each administration of Venofer. IV iron sucrose (Venofer) given as divided dosages, and low molecular weight iron dextran (CosmoFer) this can be given as divided dose or as a total dose infusion . This topic . For iron maintenance treatment, administer Venofer, (2 years of age or older) with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment. This parenteral iron replacement for iron deficiency anemia calculator determines the parenteral dose of iron supplement needed to replenish iron stores and hemoglobin levels. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Parenteral Iron Replacement For Iron Deficiency Anemia Calculator, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Clinical use of the total dose intravenous infusion of iron dextran, When is high-dose intravenous iron repletion needed? Either increases effects of the other by pharmacodynamic synergism. Applies only to oral form of both agents. Avoid or Use Alternate Drug. Applies only to oral form of both agents. FERAHEME Dosing & Administration - Feraheme FERAHEME has flexible dosing for your patients FERAHEME flexible scheduling gives your patients the freedom to receive the iron they need as early as 3 days apart 1 FLEXIBLE DILUTION OPTIONS 1 Dilute full contents of vial (17 mL) in 50 mL to 200 mL of: 0.9% NaCl, or 5% dextrose STORAGE 1 Serious - Use Alternative (1)iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. [. PDF Injectafer (ferric carboxymaltose injection) - Food and Drug Administration Found in multiple references. 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. commonly, these are generic drugs. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every two weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Do not double the dose to catch up. Minor/Significance Unknown.iron sucrose increases levels of calcium chloride by enhancing GI absorption. For patients weighing less than 50 kg (110 lb): Give Injectafer in two doses separated by at least 7 days. Chandler G, Harchowel J, Macdougall I. Last updated 28/06/2018 Enter values here and press 'Calculate'. Philadelphia, PA: Lippincott Williams & Wilkins;2013;303-307. Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Calculation of the Total Iron Deficit Alternative equation, Iron Dextran Dosing Calculator (iron deficit), HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication, Pharmacosmos A/S, CosmoFer low molecular weight (Mw) iron dextran. ------------------------------------------------------------------------- Ferric Carboxymaltose [ Injectafer ] Elemental iron: Injectafer contains 50 mg of elemental iron - 750 mg/15 mL [package insert] Indications: Injectafer is indicated for the treatment of iron deficiency anemia in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron; who have non-dialysis dependent chronic kidney disease.