2011 Mar;25(3):262-5. Skeletal Radiology. The origin of MDACL may be degenerative or traumatic. J Clin Epidemiol 62(10):10061012. Springer Nature. Knee. Before 2022 Nov 24. doi: 10.1007/s00402-022-04659-z. 4. Mucoid degeneration of the ACL is suspected when an apparently thickened and ill-defined ligament with increased signal intensity on all sequences in MRI is identified in a patient with physically intact ligament and no obvious trauma history. Clin Orthop Surg. J Orthop. MEDLINE, Embase, Google Scholar, Cochrane, ISI web of science and Scopus were comprehensively searched from the earliest year of indexing until 10 July 2020. Online ahead of print. Mucoid degeneration of the anterior cruciate ligament. 2012 Sep;46(5):561-5. doi: 10.4103/0019-5413.101037. MeSH Treatment for MDACL usually starts non-surgically with anti-inflammatory drugs and physiotherapy. Tissue biopsy was performed in 85% of patients (58 of 68) in the study of Cha et al. See this image and copyright information in PMC. Anterior cruciate ligament ganglia and mucoid degeneration: coexistence and clinical correlation. Mucoid degeneration of the anterior cruciate ligament: can platelet https://doi.org/10.1007/s00167-011-1433-0, Article https://doi.org/10.4055/cios.2018.10.3.307, University Hospitals of Derby and Burton, Uttoxeter Rd, Derby, DE22 3NE, UK, Trauma and Orthopaedic Speciality Trainee, West Midlands Deanery, Birmingham Rotation, Birmingham, UK, University Hospitals Plymouth NHS Trust, Plymouth, UK, University of Alexandria, Alexandria, Egypt, University Hospital Coventry and Warwickshire, Clifford Bridge Road, Walsgrave, Coventry, CV2 2DX, UK, You can also search for this author in Lintz F, Pujol N, Boisrenoult P, Bargoin K, Beaufils P, Dejour D. Knee Surg Sports Traumatol Arthrosc. Six studies reported using the pivot shift test; unsurprisingly, Lintz et al. Mucoid degeneration of the anterior cruciate ligament (ACL) is a very rare cause of knee pain. Furthermore, this raises the question as to whether the symptoms (pain and diminished range of movement) were solely due to MDACL and not secondary to other associated pathological conditions. It has recently been postulated that mucoid degeneration of the ACL is related to the medial knee compartment joint space loss in patients with osteoarthritis or in the OA risk group 6. Dietary management and various treatments Scanning and diagnostic . 2004;182 (5): 1283-7. . Manage cookies/Do not sell my data we use in the preference centre. PROSPERO. What you feel (symptoms) You feel heaviness in knee joint. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). In these studies, the total number of patients with a postoperative positive Lachman test was 40% (77 of 194 patients). A posterior approach will allow for the detection of changes by probing the ligament and mucoid material can be expressed. As there was no control group in any of the studies and the natural history of MDACL is not known, the postoperative improvement may have been attributed to the placebo effect, simultaneous arthroscopic procedures or the postoperative rehabilitation, or may be due to the pain having resolved without treatment at all. Sweed T, Mussa M, El-Bakoury A, Geutjens G, Metcalfe A. Knee Surg Relat Res. Accessibility Rajani AM, Shah UA, Mittal ARS, Gupta S, Garg R, Punamiya M. Knee Surg Relat Res. 2010 Jun;96(4):400-6. doi: 10.1016/j.otsr.2010.02.008. The anterior cruciate ligament (ACL) is one of the more vital and more easily injured ligaments within our knee. That is usually the journal article where the information was first stated. Accessibility Truncation means that the . proposed reduction plasty, which is reduction of the ACL to normal volume without excision of all mucoid tissue. W B Saunders Co. (2005) ISBN:0721602703. -, McIntyre J, Moelleken S, Tirman P. Mucoid degeneration of the anterior cruciate ligament mistaken for ligamentous tears. Unauthorized use of these marks is strictly prohibited. At the time the article was last revised Dai Roberts had no recorded disclosures. Bone and joint imaging. A June 2018 MRI of the cervical spine found multilevel degenerative changes of the cervical spine, most pronounced at 6-7 and small disc herniations at 5-6 and C4-5, with slight interval progression at 5-6. . Arthroscopic debridement of the mucoid degeneration of the ACL was safe and effective in the patient. Shimasaki K, Yoshioka T, Kanamori A, Yamazaki M. Case Rep Orthop. JBR-BTR. However, MDACL is asymptomatic in most patients. The need for delayed ACL reconstruction should be discussed preoperatively, especially if complete resection of the ACL is to be performed. The retrospective study by Kim et al. MDACL is differentiated from synovial cysts of the anterior cruciate ligament (ACL) where, in MDACL, mucoid tissue intermingles within ACL fibres and is not contained within a cyst [3]. -, Kumar A, Bickerstaff DR, Grimwood JS, Suvarna SK. 2013 Oct;99(6):693-7. doi: 10.1016/j.otsr.2013.04.010. Average improvement in flexion was 21.5 degrees (0 to 60 degrees). 8600 Rockville Pike Keywords: Mucoid degeneration of ACL Justamom21 Feb 17, 2023 7:27 AM Among other conditions - osteoarthritis, osteopenia, spondylolisthesis- an MRI report showed "severe mucoid degeneration of the ACL" in my left knee. Knee Surgery & Related Research Kim TH, Lee DH, Lee SH, Kim JM, Kim CW, Bin SI. Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J (2003) Methodological index for non-randomized studies (MINORS): development and validation of a new instrument. This series describes the clinicoradiological presentation of patients with mucoid ACL, partial arthroscopic debridement of ACL and outcomes. 8600 Rockville Pike Mucoid degeneration of both ACL and PCL. There is no consensus on treatment and evidence is scarce. [17] do not mention whether any patients underwent biopsy (Table 3). sharing sensitive information, make sure youre on a federal Federal government websites often end in .gov or .mil. This study concerns complete ACL resec In the nine included studies, four different scores were used for outcome assessment. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. How to Treat ACL Mucoid Degeneration? - HTQ Arch Orthop Trauma Surg. The mean age at the time of surgery was 57 years (range, 31 to 78 years). Joshita Poojary - Sports Physical Therapist - Padmanabhan's - Linkedin Skelet Radiol 30(6):312315. It often presents with progressive knee pain, restriction in range of motion without a significant history of trauma, and without knee instability. National Library of Medicine What causes mucoid degeneration of ACL? Risk factors Predisposing factors include the following 1: aging Seven of the nine studies reported using the Lachman test to check postoperative ACL laxity. The rate of simultaneous meniscectomy ranged from 13 to 44%. Intact fibers are best seen on T2WI. A historical cohort of patients who underwent arthroscopic total or partial excision of the anterior cruciate ligament due to mucoid degeneration between 2011 and 2014 were reviewed. The need for simultaneous or delayed ACL reconstruction should be discussed with patients in case total resection of the ACL is to be performed, particularly in young active patients. Conclusions. Association between magnetic resonance imaging characteristics and pathological findings in entire posterior cruciate ligament with mucoid degeneration. J Chin Med Assoc. They respond well to a judicious arthroscopic release of the ACL with notchplasty. 2021 Aug 21;33(1):26. doi: 10.1186/s43019-021-00110-6. Loganathan D, Soma Sundar S, Sundar S, Sahanand S, Rajan DV. Advanced MR imaging of the cruciate ligaments. ACL Ganglion Cysts - Radsource Does mucoid degeneration of ACL require surgery? - TimesMojo Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. You can read more if you want. proposed a different intervention called reduction plasty, whereby the hypertrophic ACL is reduced to normal size without excision of all mucoid substance [17]. Pandey, Vivek et al. 1. Indian J Orthop 48(2):197202. Download Citation | On Feb 1, 2023, O.R. A September 2018 MRI of the left knee showed anterior cruciate ligament and mucoid degeneration with intra cruciate ganglion . Besides, the patient may also have trouble in moving. 2001;17(9):E37. MRI is better at detecting mucoid degeneration than arthroscopy, as the surface of the ligament is often intact. Lintz F, Pujol N, Boisrenoult P, Bargoin K, Beaufils P, Dejour D. Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. Epub 2018 Jan 2. This ligament consists of two fibers, mainly, the anterio-medial and postero-lateral fibers, respectively. The aetiology of MDACL is not clearly understood. Mucoid degeneration of the anterior cruciate ligament: MRI, clinical, intraoperative, and histological findings. Clipboard, Search History, and several other advanced features are temporarily unavailable. Arthroscopic resection of ACL mucoid degeneration is effective for treating pain and flexion limitation, but at the expense of anterior laxity. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Epub 2013 Aug 27. The origin of MDACL may be degenerative or traumatic. Twenty-eight knees (97%) showed soft and/or delayed stops on postoperative Lachman testing. I have persistent pain in the back of that knee that is exacerbated by walking and bending it. Careers. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Federal government websites often end in .gov or .mil. Introduction Mucoid degeneration of the anterior cruciate ligament (MDACL) is a rare entity, first described by Kumar et al. There was an improvement in postoperative range of motion and outcome scores (Lysholm and International Knee Documentation Committee scores and the Knee Injury and Osteoarthritis Outcome Score). Mucoid degeneration of the ACL is suspected when an apparently thickened and ill-defined ligament with increased signal intensity on all sequences in MRI is identified in a patient with physically intact ligament and no obvious trauma history. Cookies policy. Epub 2018 Jun 13. It contrasts with cystic lesions better known as synovial cysts or intercondylar fossa cysts. Patients will . Mucoid degeneration of the anterior cruciate ligament: Management and outcome.. Instrumental treatment. Management of mucoid degeneration of the anterior cruciate ligament: a systematic . 1992;159(2):35760. ACL mucoid degeneration is an uncommon pathological condition; the pathogenesis, prevalence, and association with other intra-articular knee structural damage are still poorly understood. Results: Clin Orthop Surg. Mucoid degeneration of ACL | Mayo Clinic Connect The clinical presentation is one of posterior pain with limited flexion. Disclaimer. However, symptomatic instability was not common. Orthop Traumatol Surg Res 96(4):400406, Bergin D, Morrison WB, Carrino JA, Nallamshetty SN, Bartolozzi AR (2004) Anterior cruciate ligament ganglia and mucoid degeneration: coexistence and clinical correlation. 2018 Sep;10(3):307-314. doi: 10.4055/cios.2018.10.3.307. Its signal is increased on all sequences. 1). For treatment of this, partial removing of bulky ACL is generally done, which causes weakness of the ACL. Arthroscopic debridement of the anterior cruciate ligament (ACL) results in satisfactory pain relief and improvement in knee outcome scores. Lintz F, Pujol N, Boisrenoult P, Bargoin K, Beaufils P, Dejour D. Knee Surg Sports Traumatol Arthrosc. government site. 2022 Mar;50(3):3000605221084865. doi: 10.1177/03000605221084865. Mucoid degeneration of the anterior cruciate ligament (ACL) is a rare cause of knee pain. Kim TH, Lee DH, Lee SH, Kim JM, Kim CW, Bin SI. This is a rare pathological condition, in which, there is increased signal from within the ligament. At the time the article was created Frank Gaillard had no recorded disclosures. Disclaimer. 2012;4 (2): 167-70. MM and A performed the literature search, and data analysis. Arthroscopy. The cause is not really known, but patients usually do not complain of instability. They reported that a biopsy indicated mucoid degeneration and a relief of symptoms could be obtained through arthroscopic partial resection of the ligament. Mucoid degeneration of the anterior cruciate ligament (ACL) is a little-known entity. Anterior cruciate ligament mucoid degeneration. Treatment options include non-operative management, arthroscopic debridement with a biceps tenotomy or tenodesis, complete or partial repair, patch augmentation, superior capsular reconstruction, muscle/tendon transfer and reverse total shoulder arthroplasty. Clinical outcome was reported using a variety of scores (the Lysholm and International Knee Documentation Committee (IKDC) score, the Knee Injury and Osteoarthritis Outcome Score (KOOS) and the visual analogue scale (VAS) score) in the different studies; these are summarized in Table 4. -, Bergin D, Morrison WB, Carrino JA, Nallamshetty SN, Bartolozzi AR. 2007;15 (1): 73-86. FOIA Preoperative and postoperative results of eleven patient were compared. Methods: In this review, the mean age of patients ranged from 31 to 78years; mean age was highest in the study of Kim et al. Epidemiology The likelihood of mucoid change within ligaments and tendons increases with age 1. However, the authors did not report whether there were any other patients with symptomatic instability. (Table 3). Introduction: Mucoid degeneration of the anterior cruciate ligament (ACL) is a little-known entity. Another theory is the synovial theory whereby a pouch of synovium herniates and is subsequently filled with synovium [2]. I give my consent to Physiopedia to be in touch with me via email using the information I have provided in this form for the purpose of news, updates and marketing. : A Meta-Analysis. . Mucoid Degeneration of the Anterior Cruciate Ligament: A Case Report Mucoid degeneration of the anterior cruciate ligament (ACL) of the knee can cause knee pain and other symptoms. I get PT and acupuncture, have had several epidural injections, and am trying hard to avoid osteoporosis meds (was on bisphosphonates for many years many years ago) as well as spinal fusion. National Library of Medicine Arthroscopy. Bethesda, MD 20894, Web Policies Finally, partial meniscectomy was commonly performed simultaneously with ACL debridement in all studies, which arguably could be the reason for the postoperative improvement. Mucoid degeneration of acl (anterior cruciate ligament) is not a common problem and mostly it is found in female patients. 2022 Nov 24. doi: 10.1007/s00402-022-04659-z. Mucoid degeneration is characterized by an increase in the mucoid ground substance in the connective tissue containing glycoprotein and mucoprotein [ 4 ]. Radiologic findings associated with mucoid degeneration of the anterior cruciate ligament. Clipboard, Search History, and several other advanced features are temporarily unavailable. #radiologycpd #medicalimaging #imaging #radcme #rheumatology #arthritis #rheumatologist #orthopaedic #painphysician #physiotherapy #sportsmed #orthopaedic #mskmri. ACL MUCOID DEGENERATION RADIOLOGY MRI - Radedasia The purpose of this study was to investigate the outcomes of management of mucoid degeneration of the anterior cruciate ligament (MDACL) by performing a systematic review of methods of treatment that have been reported. Patients and methods: Bethesda, MD 20894, Web Policies The site is secure. Exclusion criteria were (1) case reports, literature reviews and conference abstracts and (2) studies written in languages other than English. Data extracted included mean age and gender of the patients, duration of follow up, associated chondral and meniscal lesions, interventions and outcomes. J Orthop. Any discrepancy was resolved by the senior author. This infiltrating lesion is included in the mucoid pathology of the intercondylar fossa. Mucoid degeneration,: like degenerative arthritis of a joint, generally occurs as a results of aging. Posterior pain disappeared in 27 cases (93%), on average 3.7 weeks after the procedure. A positive Lachman test and a negative pivot shift were noted after surgery in all cases. Mucoid degeneration of the anterior cruciate ligament (MD-ACL) was first characterized by Kumar et al. Would you like email updates of new search results? Background: Mucoid degeneration of the anterior cruciate ligament (ACL) is an uncommon non-traumatic cause of knee pain and motion restriction, typically seen in a middle-aged population. Online ahead of print. Cite this article. MeSH Management of mucoid degeneration of the anterior cruciate ligament: a systematic review. Partial/Total ACL resection arthroscopically- There is marked improvement in the range and reduced posterior pain, but at the cost of increased post-operative knee laxity. 2011 Jun;25(6):650-2. Meniscectomy was undertaken in 11 cases (41%). Sometimes, it is mislead as ACL tear on MRI findings, hence requires probing and histopathology for definitive diagnosis. Mucoid degeneration of the ACL is suspected when an apparently thickened and ill-defined ligament with increased signal intensity on all sequences in MRI is identified in a patient with physically intact ligament and no obvious trauma history. Conclusions: Mucoid degeneration of the ACL is a clinical condition afflicting active middle-aged people without a single significant traumatic episode with a specific MRI picture. The aim of this study was to detail the clinical, radiological, arthroscopic, and pathological findings of mucoid degeneration of the anterior cruciate ligament and report the clinical outcomes following arthroscopic treatment. All nine studies included patients with symptomatic MDACL confirmed by MRI (Table3). 1 Its prevalence in magnetic resonance imaging (MRI) is 1.8-5.3%, but not all lesions are symptomatic.2, 3 It is characterized by infiltration of mucoid-like substance (glycosaminoglycans) interspersed within the Khanna et al. Increased posterior slope and coronal inclination of the tibial joint Hypothesis: Reduction plasty for hypertrophic anterior cruciate ligament mucoid degeneration: clinical and knee laxity outcomes in 23 cases. Epub 2008 Dec 17. Knee Surg Sports Traumatol Arthrosc 19(8):13261333. The https:// ensures that you are connecting to the Due to the lack of specific symptoms and signs, its diagnosis is often delayed or even misdiagnosed in clinical practice [ [1] , [2] ]. Would you like email updates of new search results? 2001;30(6):312315. Would you like email updates of new search results? Its interstitial nature within the ACL structure contrasts with synovial cyst of the ACL. J Bone Joint Surg Br. -, Makino A, Pascual-Garrido C, Rolon A, Isola M, Muscolo DL. Anterior Cruciate Ligament (ACL) MRI: Practice Essentials, Anatomy mucoid degeneration acl symptoms. If you believe that this Physiopedia article is the primary source for the information you are refering to, you can use the button below to access a related citation statement. Symptomatic ACL mucoid degeneration in middle-age athletes. Hamal B, Karmacharya M, Mangal Joshi K, Gorkhali R. J Nepal Health Res Counc. Anterior cruciate ligament (ACL) mucoid degeneration, along with tears and anterior cruciate ligament ganglion cysts, is a relatively common cause of increased signal within the anterior cruciate ligament (ACL ). Level of evidence: Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. Chudasama et al. 3. Fourteen knees (48%) had limited flexion, on average 97 degrees. 2. Results: in this condition your acl (anterior cruciate ligament) filled with jelly like material and it thickened so space in intercondylar resion of knee joint is reduced. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. "Traumatic theory - post injury, ACL fibroblasts secrete glycosaminoglycans, the mucin substance within the ACL. Epub 2011 Feb 18. Seventeen females (67%) and eight males (33%) were included in the final analysis. -, Hodler J, Haghighi P, Trudell D, Resnick D. The cruciate ligaments of the knee: Correlation between MR appearance and gross and histologic findings in cadaveric specimens. Radiologic findings associated with mucoid degeneration of the anterior cruciate ligament. 2011 Aug;19(8):1326-33. doi: 10.1007/s00167-011-1433-0. Anatomopathology samples were collected in 18 cases. Bookshelf Arthroscopy. Introduction Mucoid degeneration of the anterior cruciate ligament (ACL) is a little-known pathology. Introduction to Arthroscopic Debridement Mucoid degeneration of A C L is more common and literature has also reported many cases, but for PCL only few cases have been reported in English literature. government site. Introduction: 1173185. See this image and copyright information in PMC. I have multiple issues - spondylolisthesis in L4/L5 and L5/S1, osteopenia and osteoarthritis. Keywords: mucoid degeneration, anterior cruciate ligament, acl reconstruction, arthroscopy, knee Along with that, it also controls the internal rotation. Possible etiologies include: It is postulated that mucoid degeneration may be a predisposing factor in the formation of ACL ganglion cysts. No reconstruction was performed at the same time. Unauthorized use of these marks is strictly prohibited. The https:// ensures that you are connecting to the 42 Mucoid degeneration of the anterior cruciate ligament with erosion of the lateral femoral condyle P. Melloni, R. Valls, M. Yuguero, A. Saez Medicine Sweed, T., Mussa, M., El-Bakoury, A. et al. [Diagnosis and treatment of anterior cruciate ligament cysts]. Mucoid Degeneration of Posterior Cruciate Ligament with Secondary